NOW Ultra Omega-3 softgels contain 500 EPA and 250 DHA. The natural fish oil concentrate used in this softgel is manufactured under strict quality control standards. It is tested to be free of potentially harmful levels of contaminants (i.e. mercury, heavy metals, PCB’s, dioxins, and other contaminants). Those who experience nausea or reflux from other fish oils should find this enteric coated, odor-controlled softgel easier to tolerate. From the FDA: "Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease." Take 1 softgel 1 to 2 times daily with food.